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Pectenotoxin-2 from Marine Sponges: A Potential Anti-Cancer Agent—A Review

Pectenotoxin-2 (PTX-2), which was first identified as a cytotoxic entity in marine sponges, has been reported to display significant cytotoxicity to human cancer cells where it inhibits mitotic separation and cytokinesis through the depolymerization of actin filaments. In the late stage of endoredup...

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Detalles Bibliográficos
Autores principales: Kim, Gi-Young, Kim, Wun-Jae, Choi, Yung Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229229/
https://www.ncbi.nlm.nih.gov/pubmed/22163180
http://dx.doi.org/10.3390/md9112176