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Engineering an L-cell line that expresses insulin under the control of the glucagon-like peptide-1 promoter for diabetes treatment

BACKGROUND: Diabetes mellitus is a complicated disease with a pathophysiology that includes hyperinsulinemia, hyperglycemia and other metabolic impairments leading to many clinical complications. It is necessary to develop appropriate treatments to manage the disease and reduce possible acute and ch...

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Detalles Bibliográficos
Autores principales: Rasouli, Mina, Ahmad, Zalinah, Omar, Abdul Rahman, Allaudin, Zeenathul N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229441/
https://www.ncbi.nlm.nih.gov/pubmed/22047106
http://dx.doi.org/10.1186/1472-6750-11-99