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Reduced inflammation accompanies diminished myelin damage and repair in the NG2 null mouse spinal cord

BACKGROUND: Multiple sclerosis (MS) is a demyelinating disease in which blood-derived immune cells and activated microglia damage myelin in the central nervous system. While oligodendrocyte progenitor cells (OPCs) are essential for generating oligodendrocytes for myelin repair, other cell types also...

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Detalles Bibliográficos
Autores principales: Kucharova, Karolina, Chang, Yunchao, Boor, Andrej, Yong, Voon Wee, Stallcup, William B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229456/
https://www.ncbi.nlm.nih.gov/pubmed/22078261
http://dx.doi.org/10.1186/1742-2094-8-158