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Improving the Alignment Quality of Consistency Based Aligners with an Evaluation Function Using Synonymous Protein Words

Most sequence alignment tools can successfully align protein sequences with higher levels of sequence identity. The accuracy of corresponding structure alignment, however, decreases rapidly when considering distantly related sequences (<20% identity). In this range of identity, alignments optimiz...

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Detalles Bibliográficos
Autores principales: Lin, Hsin-Nan, Notredame, Cédric, Chang, Jia-Ming, Sung, Ting-Yi, Hsu, Wen-Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229492/
https://www.ncbi.nlm.nih.gov/pubmed/22163274
http://dx.doi.org/10.1371/journal.pone.0027872