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Improving the Alignment Quality of Consistency Based Aligners with an Evaluation Function Using Synonymous Protein Words
Most sequence alignment tools can successfully align protein sequences with higher levels of sequence identity. The accuracy of corresponding structure alignment, however, decreases rapidly when considering distantly related sequences (<20% identity). In this range of identity, alignments optimiz...
Autores principales: | Lin, Hsin-Nan, Notredame, Cédric, Chang, Jia-Ming, Sung, Ting-Yi, Hsu, Wen-Lian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229492/ https://www.ncbi.nlm.nih.gov/pubmed/22163274 http://dx.doi.org/10.1371/journal.pone.0027872 |
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