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Crosstalk between JNK and SUMO Signaling Pathways: deSUMOylation Is Protective against H(2)O(2)-Induced Cell Injury
BACKGROUND: Oxidative stress is a key feature in the pathogenesis of several neurological disorders. Following oxidative stress stimuli a wide range of pathways are activated and contribute to cellular death. The mechanism that couples c-Jun N-terminal kinase (JNK) signaling, a key pathway in stress...
Autores principales: | Feligioni, Marco, Brambilla, Elisa, Camassa, Agata, Sclip, Alessandra, Arnaboldi, Andrea, Morelli, Federica, Antoniou, Xanthi, Borsello, Tiziana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229511/ https://www.ncbi.nlm.nih.gov/pubmed/22164242 http://dx.doi.org/10.1371/journal.pone.0028185 |
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