Brachyury and Related Tbx Proteins Interact with the Mixl1 Homeodomain Protein and Negatively Regulate Mixl1 Transcriptional Activity

Mixl1 is a homeodomain transcription factor required for mesoderm and endoderm patterning during mammalian embryogenesis. Despite its crucial function in development, co-factors that modulate the activity of Mixl1 remain poorly defined. Here we report that Mixl1 interacts physically and functionally...

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Detalles Bibliográficos
Autores principales: Pereira, Lloyd A., Wong, Michael S., Lim, Sue Mei, Sides, Alexandra, Stanley, Edouard G., Elefanty, Andrew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229578/
https://www.ncbi.nlm.nih.gov/pubmed/22164283
http://dx.doi.org/10.1371/journal.pone.0028394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229578/
https://www.ncbi.nlm.nih.gov/pubmed/22164283
http://dx.doi.org/10.1371/journal.pone.0028394

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