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Autophagy Inhibition Enhances Daunorubicin-Induced Apoptosis in K562 Cells
Anthracycline daunorubicin (DNR) is one of the major antitumor agents widely used in the treatment of myeloid leukemia. Unfortunately, the clinical efficacy of DNR was limited because of its cytotoxity at high dosage. As a novel cytoprotective mechanism for tumor cell to survive under unfavorable co...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229606/ https://www.ncbi.nlm.nih.gov/pubmed/22164300 http://dx.doi.org/10.1371/journal.pone.0028491 |