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Autophagy Inhibition Enhances Daunorubicin-Induced Apoptosis in K562 Cells

Anthracycline daunorubicin (DNR) is one of the major antitumor agents widely used in the treatment of myeloid leukemia. Unfortunately, the clinical efficacy of DNR was limited because of its cytotoxity at high dosage. As a novel cytoprotective mechanism for tumor cell to survive under unfavorable co...

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Detalles Bibliográficos
Autores principales: Han, Weidong, Sun, Jie, Feng, Lifeng, Wang, KaiFeng, Li, Da, Pan, Qin, Chen, Yan, Jin, Wei, Wang, Xian, Pan, Hongming, Jin, Hongchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229606/
https://www.ncbi.nlm.nih.gov/pubmed/22164300
http://dx.doi.org/10.1371/journal.pone.0028491