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Expression pattern of class I histone deacetylases in vulvar intraepithelial neoplasia and vulvar cancer: a tissue microarray study

BACKGROUND: Epigenetic regulation is an important mechanism leading to cancer initiation and promotion. Histone acetylation by histone deacetylases (HDACs) represents an important part of it. The development of HDAC inhibitors has identified the utility of HDACs as a therapeutic target. Little is kn...

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Detalles Bibliográficos
Autores principales: Samartzis, Nicolas, Imesch, Patrick, Dedes, Konstantin J, Samartzis, Eleftherios P, Fedier, André, Fink, Daniel, Caduff, Rosmarie, Fehr, Mathias K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229619/
https://www.ncbi.nlm.nih.gov/pubmed/22029821
http://dx.doi.org/10.1186/1471-2407-11-463