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Image-Based Genome-Wide siRNA Screen Identifies Selective Autophagy Factors

Selective autophagy involves the recognition and targeting of specific cargo, such as damaged organelles, misfolded proteins, or invading pathogens for lysosomal destruction(1–4). Yeast genetic screens have identified proteins required for different forms of selective autophagy, including cytoplasm-...

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Detalles Bibliográficos
Autores principales: Orvedahl, Anthony, Sumpter, Rhea, Xiao, Guanghua, Ng, Aylwin, Zou, Zhongju, Tang, Yi, Narimatsu, Masahiro, Gilpin, Christopher, Sun, Qihua, Roth, Michael, Forst, Christian V., Wrana, Jeffrey L., Zhang, Ying E., Luby-Phelps, Katherine, Xavier, Ramnik, Xie, Yang, Levine, Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229641/
https://www.ncbi.nlm.nih.gov/pubmed/22020285
http://dx.doi.org/10.1038/nature10546