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Image-Based Genome-Wide siRNA Screen Identifies Selective Autophagy Factors
Selective autophagy involves the recognition and targeting of specific cargo, such as damaged organelles, misfolded proteins, or invading pathogens for lysosomal destruction(1–4). Yeast genetic screens have identified proteins required for different forms of selective autophagy, including cytoplasm-...
Autores principales: | Orvedahl, Anthony, Sumpter, Rhea, Xiao, Guanghua, Ng, Aylwin, Zou, Zhongju, Tang, Yi, Narimatsu, Masahiro, Gilpin, Christopher, Sun, Qihua, Roth, Michael, Forst, Christian V., Wrana, Jeffrey L., Zhang, Ying E., Luby-Phelps, Katherine, Xavier, Ramnik, Xie, Yang, Levine, Beth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229641/ https://www.ncbi.nlm.nih.gov/pubmed/22020285 http://dx.doi.org/10.1038/nature10546 |
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