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Expression, Localization, and Phosphorylation of Akt1 in Benign and Malignant Thyroid Lesions
The serine/threonine protein kinase Akt is a key molecule in the phosphatidyl inositol 3-kinase pathway that is often overactivated in human cancers. Three Akt isoforms (Akt1, Akt2, Akt3) have been identified in human cells and they show different distribution and have non-redundant functions. The a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229690/ https://www.ncbi.nlm.nih.gov/pubmed/21898122 http://dx.doi.org/10.1007/s12022-011-9177-4 |