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Expression, Localization, and Phosphorylation of Akt1 in Benign and Malignant Thyroid Lesions

The serine/threonine protein kinase Akt is a key molecule in the phosphatidyl inositol 3-kinase pathway that is often overactivated in human cancers. Three Akt isoforms (Akt1, Akt2, Akt3) have been identified in human cells and they show different distribution and have non-redundant functions. The a...

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Detalles Bibliográficos
Autores principales: Krześlak, Anna, Pomorski, Lech, Lipińska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229690/
https://www.ncbi.nlm.nih.gov/pubmed/21898122
http://dx.doi.org/10.1007/s12022-011-9177-4