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Understanding the complex mechanisms of β(2)-microglobulin amyloid assembly

Several protein misfolding diseases are associated with the conversion of native proteins into ordered protein aggregates known as amyloid. Studies of amyloid assemblies have indicated that non-native proteins are responsible for initiating aggregation in vitro and in vivo. Despite the importance of...

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Detalles Bibliográficos
Autores principales: Eichner, Timo, Radford, Sheena E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229708/
https://www.ncbi.nlm.nih.gov/pubmed/21595827
http://dx.doi.org/10.1111/j.1742-4658.2011.08186.x