Two sides to every story: the HIF-dependent and HIF-independent functions of pVHL

von Hippel–Lindau (VHL) disease is a hereditary cancer syndrome caused by inherited mutations that inactivate the VHL tumour suppressor gene. The VHL locus encodes pVHL, whose best studied function is to bind to and down-regulate the hypoxia-inducible factor (HIF) family of oxygen-dependent transcri...

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Detalles Bibliográficos
Autores principales: Li, Mingqing, Kim, William Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229769/
https://www.ncbi.nlm.nih.gov/pubmed/21155973
http://dx.doi.org/10.1111/j.1582-4934.2010.01238.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229769/
https://www.ncbi.nlm.nih.gov/pubmed/21155973
http://dx.doi.org/10.1111/j.1582-4934.2010.01238.x

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