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Kaurenic acid: Evaluation of the in vivo and in vitro antitumor activity on murine melanoma

OBJECTIVE: The in vivo and in vitro antitumor activity of kaurenic acid [kaur 16-en-19 oic acid] (KA) in melanoma was evaluated in a murine model in comparison with taxol (Tx). MATERIALS AND METHODS: B16F1 melanoma was developed in C57BL/6 mice and cell cultures. Survival test, tumor growth, dissect...

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Detalles Bibliográficos
Autores principales: Sosa-Sequera, Miriam C., Chiurillo, Miguel, Moscoso, Jaime, Dolinar, Josefina, Suarez, Omar, Neira, Natalia, Mendoza, Hernan, Rivero-Paris, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229785/
https://www.ncbi.nlm.nih.gov/pubmed/22144774
http://dx.doi.org/10.4103/0253-7613.89826