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Alternative Splicing of CARMA2/CARD14 Transcripts Generates Protein Variants With Differential Effect on NF-κB Activation and Endoplasmic Reticulum Stress-Induced Cell Death

The caspase recruitment domain (CARD)-containing proteins CARMA1-3 share high degree of sequence, structure and functional homology. Whereas CARMA1 and CARMA3 have been identified as crucial components of signal transduction pathways that lead to activation of NF-κB transcription factor, little is k...

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Detalles Bibliográficos
Autores principales: Scudiero, Ivan, Zotti, Tiziana, Ferravante, Angela, Vessichelli, Mariangela, Vito, Pasquale, Stilo, Romania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229840/
https://www.ncbi.nlm.nih.gov/pubmed/21302310
http://dx.doi.org/10.1002/jcp.22667