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Evolutionary Modeling of Combination Treatment Strategies To Overcome Resistance to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer

[Image: see text] Many initially successful anticancer therapies lose effectiveness over time, and eventually, cancer cells acquire resistance to the therapy. Acquired resistance remains a major obstacle to improving remission rates and achieving prolonged disease-free survival. Consequently, novel...

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Detalles Bibliográficos
Autores principales: Mumenthaler, Shannon M., Foo, Jasmine, Leder, Kevin, Choi, Nathan C., Agus, David B., Pao, William, Mallick, Parag, Michor, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230244/
https://www.ncbi.nlm.nih.gov/pubmed/21995722
http://dx.doi.org/10.1021/mp200270v