Deficiency of Multidrug and Toxin Extrusion 1 Enhances Renal Accumulation of Paraquat and Deteriorates Kidney Injury in Mice

[Image: see text] Multidrug and toxin extrusion 1 (MATE1/solute carrier 47A1) mediates cellular transport of a variety of structurally diverse compounds. Paraquat (PQ), which has been characterized in vitro as a MATE1 substrate, is a widely used herbicide and can cause severe toxicity to humans afte...

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Detalles Bibliográficos
Autores principales: Li, Qing, Peng, Xiujuan, Yang, Hyekyung, Wang, Hongbing, Shu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230245/
https://www.ncbi.nlm.nih.gov/pubmed/21991918
http://dx.doi.org/10.1021/mp200395f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230245/
https://www.ncbi.nlm.nih.gov/pubmed/21991918
http://dx.doi.org/10.1021/mp200395f

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