Small molecule inhibitors reveal Niemann-Pick C1 is essential for ebolavirus infection

Ebolavirus (EboV) is a highly pathogenic enveloped virus that causes outbreaks of zoonotic infection in Africa. The clinical symptoms are manifestations of the massive production of pro-inflammatory cytokines in response to infection(1) and in many outbreaks, mortality exceeds 75%. The unpredictable...

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Detalles Bibliográficos
Autores principales: Côté, Marceline, Misasi, John, Ren, Tao, Bruchez, Anna, Lee, Kyungae, Filone, Claire Marie, Hensley, Lisa, Li, Qi, Ory, Daniel, Chandran, Kartik, Cunningham, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230319/
https://www.ncbi.nlm.nih.gov/pubmed/21866101
http://dx.doi.org/10.1038/nature10380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230319/
https://www.ncbi.nlm.nih.gov/pubmed/21866101
http://dx.doi.org/10.1038/nature10380

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