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Interaction of an anticancer peptide fragment of azurin with p53 and its isolated domains studied by atomic force spectroscopy

p28 is a 28-amino acid peptide fragment of the cupredoxin azurin derived from Pseudomonas aeruginosa that preferentially penetrates cancerous cells and arrests their proliferation in vitro and in vivo. Its antitumor activity reportedly arises from post-translational stabilization of the tumor suppre...

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Detalles Bibliográficos
Autores principales: Bizzarri, Anna Rita, Santini, Simona, Coppari, Emilia, Bucciantini, Monica, Di Agostino, Silvia, Yamada, Tohru, Beattie, Craig W, Cannistraro, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230568/
https://www.ncbi.nlm.nih.gov/pubmed/22162658
http://dx.doi.org/10.2147/IJN.S26155