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Interaction of an anticancer peptide fragment of azurin with p53 and its isolated domains studied by atomic force spectroscopy
p28 is a 28-amino acid peptide fragment of the cupredoxin azurin derived from Pseudomonas aeruginosa that preferentially penetrates cancerous cells and arrests their proliferation in vitro and in vivo. Its antitumor activity reportedly arises from post-translational stabilization of the tumor suppre...
Autores principales: | Bizzarri, Anna Rita, Santini, Simona, Coppari, Emilia, Bucciantini, Monica, Di Agostino, Silvia, Yamada, Tohru, Beattie, Craig W, Cannistraro, Salvatore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230568/ https://www.ncbi.nlm.nih.gov/pubmed/22162658 http://dx.doi.org/10.2147/IJN.S26155 |
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