Hydrophobic ion pairing of an insulin-sodium deoxycholate complex for oral delivery of insulin

Insulin was complexed with sodium deoxycholate to form an insulin-sodium deoxycholate complex (Ins-SD-Comp) using an hydrophobic ion pairing method in aqueous phase to enhance the liposolubility of insulin. In order to obtain the maximal complexation efficiency, the molar ratio of sodium deoxycholat...

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Detalles Bibliográficos
Autores principales: Sun, Shaoping, Liang, Na, Kawashima, Yoshiaki, Xia, Dengning, Cui, Fude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230571/
https://www.ncbi.nlm.nih.gov/pubmed/22162661
http://dx.doi.org/10.2147/IJN.S26450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230571/
https://www.ncbi.nlm.nih.gov/pubmed/22162661
http://dx.doi.org/10.2147/IJN.S26450

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