Cargando…

Hydrophobic ion pairing of an insulin-sodium deoxycholate complex for oral delivery of insulin

Insulin was complexed with sodium deoxycholate to form an insulin-sodium deoxycholate complex (Ins-SD-Comp) using an hydrophobic ion pairing method in aqueous phase to enhance the liposolubility of insulin. In order to obtain the maximal complexation efficiency, the molar ratio of sodium deoxycholat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Shaoping, Liang, Na, Kawashima, Yoshiaki, Xia, Dengning, Cui, Fude
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2011
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230571/ https://www.ncbi.nlm.nih.gov/pubmed/22162661 http://dx.doi.org/10.2147/IJN.S26450

Ejemplares similares

Multifunctional Composite Microcapsules for Oral Delivery of Insulin
por: Sun, Shaoping, et al.
Publicado: (2016)

Amphiphilic Polymeric Micelles Based on Deoxycholic Acid and Folic Acid Modified Chitosan for the Delivery of Paclitaxel
por: Li, Liang, et al.
Publicado: (2018)

pH-sensitive poly(lactide-co-glycolide) nanoparticle composite microcapsules for oral delivery of insulin
por: Sun, Shaoping, et al.
Publicado: (2015)

Design and Evaluation of Hydrophobic Ion Paired Insulin Loaded Self Micro-Emulsifying Drug Delivery System for Oral Delivery
por: Mudassir, Jahanzeb, et al.
Publicado: (2023)

Facilitated Buccal Insulin Delivery via Hydrophobic Ion-Pairing Approach: In vitro and ex vivo Evaluation
por: Bashyal, Santosh, et al.
Publicado: (2021)

A Chitosan-Based Micellar System as Nanocarrier For the Delivery of Paclitaxel
por: Han, Yang, et al.
Publicado: (2020)

Layered Double Hydroxide Modified with Deoxycholic and Hyaluronic Acids for Efficient Oral Insulin Absorption
por: Huang, Xia, et al.
Publicado: (2021)

Enhanced oral absorption of insulin: hydrophobic ion pairing and a self-microemulsifying drug delivery system using a D-optimal mixture design
por: Goo, Yoon Tae, et al.
Publicado: (2022)

Evaluation of Hydrophobic Nanoparticulate Delivery System for Insulin
por: Singnurkar, P. S., et al.
Publicado: (2008)

Improvement of oral availability of ginseng fruit saponins by a proliposome delivery system containing sodium deoxycholate
por: Hao, Fei, et al.
Publicado: (2016)

Development of Liposome containing sodium deoxycholate to enhance oral bioavailability of itraconazole
por: Li, Zhenbao, et al.
Publicado: (2017)

Topical formulation of sodium deoxycholate for submental lipolysis
por: Park, Hye Jeong, et al.
Publicado: (2023)

Intestinal transport mechanism and in vivo anticancer efficacy of a solid oral formulation incorporating an ion-pairing complex of pemetrexed with deoxycholic acid derivative
por: Pangeni, Rudra, et al.
Publicado: (2019)

Sodium deoxycholate-decorated zein nanoparticles for a stable colloidal drug delivery system
por: Gagliardi, Agnese, et al.
Publicado: (2018)

Enhanced oral absorption of pemetrexed by ion-pairing complex formation with deoxycholic acid derivative and multiple nanoemulsion formulations: preparation, characterization, and in vivo oral bioavailability and anticancer effect
por: Pangeni, Rudra, et al.
Publicado: (2018)

Interaction of deoxycholate with the sodium channel of squid axon membranes
Publicado: (1980)

Nanolayer encapsulation of insulin-chitosan complexes improves efficiency of oral insulin delivery
por: Song, Lei, et al.
Publicado: (2014)

A nanoemulsion/micelles mixed nanosystem for the oral administration of hydrophobically modified insulin
por: Santalices, Irene, et al.
Publicado: (2021)

In vitro synergy between sodium deoxycholate and furazolidone against enterobacteria
por: Le, Vuong Van Hung, et al.
Publicado: (2020)

Complex Polysaccharide-Based Nanocomposites for Oral Insulin Delivery
por: Collado-González, Mar, et al.
Publicado: (2020)

Self-emulsifying drug delivery systems: A versatile approach to enhance the oral delivery of BCS class III drug via hydrophobic ion pairing
por: Asad, Muhammad, et al.
Publicado: (2023)

Material design for oral insulin delivery
por: Ji, Kangfan, et al.
Publicado: (2023)

Sodium alginate microencapsulation improves the short-term oral bioavailability of cannabidiol when administered with deoxycholic acid
por: Majimbi, Maimuna, et al.
Publicado: (2021)

Insulin Inclusion into a Tragacanth Hydrogel: An Oral Delivery System for Insulin
por: Nur, Mokhamad, et al.
Publicado: (2018)

Structural modulation of insulin by hydrophobic and hydrophilic molecules
por: Begum, Shahnaz, et al.
Publicado: (2023)

Correction to: A nanoemulsion/micelles mixed nanosystem for the oral administration of hydrophobically modified insulin
por: Santalices, Irene, et al.
Publicado: (2021)

Synthesis and Plasmonic Chiroptical Studies of Sodium Deoxycholate Modified Silver Nanoparticles
por: Wang, Jing, et al.
Publicado: (2018)

Evaluation of sodium deoxycholate as solubilization buffer for oil palm proteomics analysis
por: Lau, Benjamin Yii Chung, et al.
Publicado: (2019)

Luminescent Sodium Deoxycholate Ionogel Induced by Eu(3+) in Ethylammonium Nitrate
por: Li, Xueyuan, et al.
Publicado: (2019)

Polymeric Micelles Based on Modified Glycol Chitosan for Paclitaxel Delivery: Preparation, Characterization and Evaluation
por: Liang, Na, et al.
Publicado: (2018)

Intestinal mucoadhesive devices for oral delivery of insulin
por: Banerjee, Amrita, et al.
Publicado: (2016)

Versatile Oral Insulin Delivery Nanosystems: From Materials to Nanostructures
por: Wang, Mengjie, et al.
Publicado: (2022)

Paclitaxel-loaded sodium deoxycholate-stabilized zein nanoparticles: characterization and in vitro cytotoxicity
por: Gagliardi, Agnese, et al.
Publicado: (2019)

Effects of polymers on the properties of hydrogels constructed using sodium deoxycholate and amino acid
por: Guo, Yi, et al.
Publicado: (2018)

Insulin-Loaded Barium Salt Particles Facilitate Oral Delivery of Insulin in Diabetic Rats
por: Zaman, Rahela, et al.
Publicado: (2020)

Hydrophobic ion pairing: encapsulating small molecules, peptides, and proteins into nanocarriers
por: Ristroph, Kurt D., et al.
Publicado: (2019)

The cocarcinogenic effect of intrarectal deoxycholate in rats is reduced by oral metronidazole.
por: Rainey, J. B., et al.
Publicado: (1984)

Mechanisms of deformable nanovesicles based on insulin-phospholipid complex for enhancing buccal delivery of insulin
por: Xu, You, et al.
Publicado: (2018)

Oral insulin delivery by means of solid lipid nanoparticles
por: Sarmento, Bruno, et al.
Publicado: (2007)

Novel PLGA-based nanoparticles for the oral delivery of insulin
por: Malathi, Sampath, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_utggdll7a39n46ntc3ldrlm8ir