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AcrB Trimer Stability and Efflux Activity, Insight from Mutagenesis Studies

The multidrug transporter AcrB in Escherichia coli exists and functions as a homo-trimer. The assembly process of obligate membrane protein oligomers, including AcrB, remains poorly understood. In a previous study, we have shown that individual AcrB subunit is capable of folding independently, sugge...

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Detalles Bibliográficos
Autores principales: Yu, Linliang, Lu, Wei, Wei, Yinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230630/
https://www.ncbi.nlm.nih.gov/pubmed/22163011
http://dx.doi.org/10.1371/journal.pone.0028390