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Tel1(ATM) and Rad3(ATR) kinases promote Ccq1-Est1 interaction to maintain telomeres in fission yeast

The shelterin complex plays both positive and negative roles in telomerase regulation. While shelterin prevents the checkpoint kinases ATM and ATR from fully activating DNA damage responses at telomeres, those kinases are also required for telomere maintenance. In fission yeast, cells lacking both T...

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Detalles Bibliográficos
Autores principales: Moser, Bettina A., Chang, Ya-Ting, Kosti, Jorgena, Nakamura, Toru M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230746/
https://www.ncbi.nlm.nih.gov/pubmed/22101932
http://dx.doi.org/10.1038/nsmb.2187