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Tel1(ATM) and Rad3(ATR) kinases promote Ccq1-Est1 interaction to maintain telomeres in fission yeast
The shelterin complex plays both positive and negative roles in telomerase regulation. While shelterin prevents the checkpoint kinases ATM and ATR from fully activating DNA damage responses at telomeres, those kinases are also required for telomere maintenance. In fission yeast, cells lacking both T...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230746/ https://www.ncbi.nlm.nih.gov/pubmed/22101932 http://dx.doi.org/10.1038/nsmb.2187 |