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NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling

NSP and Cas family proteins form multidomain signaling platforms that mediate cell migration and invasion through a collection of distinct signaling motifs. Members of each family interact via their respective C-terminal domains, but the mechanism of this association has remained enigmatic. Here we...

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Detalles Bibliográficos
Autores principales: Mace, Peter D., Wallez, Yann, Dobaczewska, Małgorzata K., Lee, JeongEun J., Robinson, Howard, Pasquale, Elena B., Riedl, Stefan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230775/
https://www.ncbi.nlm.nih.gov/pubmed/22081014
http://dx.doi.org/10.1038/nsmb.2152