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Use of a Multiplexed CMOS Microarray to Optimize and Compare Oligonucleotide Binding to DNA Probes Synthesized or Immobilized on Individual Electrodes

The CombiMatrix microarray with 12,544 electrodes supports in situ electrochemical synthesis of user-defined DNA probes. As an alternative, we immobilized commercially synthesized DNA probes on individual electrodes coated with electropolymerized polypyrrole (Ppy). Hybridization was measured using a...

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Detalles Bibliográficos
Autores principales: Maurer, Karl, Yazvenko, Nina, Wilmoth, Jodi, Cooper, John, Lyon, Wanda, Danley, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3231185/
https://www.ncbi.nlm.nih.gov/pubmed/22163607
http://dx.doi.org/10.3390/s100807371