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Molecular Biosensing Mechanisms in the Spleen for the Removal of Aged and Damaged Red Cells from the Blood Circulation

Heinz bodies are intraerythrocytic inclusions of hemichrome formed as a result of hemoglobin (Hb) oxidation. They typically develop in aged red cells. Based on the hypothesis that hemichrome formation is an innate characteristic of physiologically normal Hb molecules, we present an overview of our p...

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Detalles Bibliográficos
Autores principales: Sugawara, Yoshiaki, Hayashi, Yuko, Shigemasa, Yuki, Abe, Yoko, Ohgushi, Ikumi, Ueno, Eriko, Shimamoto, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3231191/
https://www.ncbi.nlm.nih.gov/pubmed/22163593
http://dx.doi.org/10.3390/s100807099