Human Thrombin Detection Through a Sandwich Aptamer Microarray: Interaction Analysis in Solution and in Solid Phase

We have developed an aptamer-based microarray for human thrombin detection exploiting two non-overlapping DNA thrombin aptamers recognizing different exosites of the target protein. The 15-mer aptamer (TBA1) binds the fibrinogen-binding site, whereas the 29-mer aptamer (TBA2) binds the heparin bindi...

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Detalles Bibliográficos
Autores principales: Sosic, Alice, Meneghello, Anna, Cretaio, Erica, Gatto, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3231252/
https://www.ncbi.nlm.nih.gov/pubmed/22163703
http://dx.doi.org/10.3390/s111009426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3231252/
https://www.ncbi.nlm.nih.gov/pubmed/22163703
http://dx.doi.org/10.3390/s111009426

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