Differential genetic interactions between Sgs1, DNA-damage checkpoint components and DNA repair factors in the maintenance of chromosome stability

BACKGROUND: Genome instability is associated with human cancers and chromosome breakage syndromes, including Bloom's syndrome, caused by inactivation of BLM helicase. Numerous mutations that lead to genome instability are known, yet how they interact genetically is poorly understood. RESULTS: W...

Descripción completa

Detalles Bibliográficos
Autores principales: Doerfler, Lillian, Harris, Lorena, Viebranz, Emilie, Schmidt, Kristina H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3231943/
https://www.ncbi.nlm.nih.gov/pubmed/22040455
http://dx.doi.org/10.1186/2041-9414-2-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3231943/
https://www.ncbi.nlm.nih.gov/pubmed/22040455
http://dx.doi.org/10.1186/2041-9414-2-8

Ejemplares similares