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Haptoglobin genotype predicts development of coronary artery calcification in a prospective cohort of patients with type 1 diabetes

BACKGROUND: Coronary artery disease has been linked with genotypes for haptoglobin (Hp) which modulates extracorpuscular hemoglobin. We hypothesized that the Hp genotype would predict progression of coronary artery calcification (CAC), a marker of subclinical atherosclerosis. METHODS: CAC was measur...

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Detalles Bibliográficos
Autores principales: Simpson, Melissa, Snell-Bergeon, Janet K, Kinney, Gregory L, Lache, Orit, Miller-Lotan, Rachel, Anbinder, Yefim, Rewers, Marian J, Levy, Andrew P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3231951/
https://www.ncbi.nlm.nih.gov/pubmed/22098782
http://dx.doi.org/10.1186/1475-2840-10-99