Cargando…

Inferring pleiotropy by network analysis: linked diseases in the human PPI network

BACKGROUND: Earlier, we identified proteins connecting different disease proteins in the human protein-protein interaction network and quantified their mediator role. An analysis of the networks of these mediators shows that proteins connecting heart disease and diabetes largely overlap with the one...

Descripción completa

Detalles Bibliográficos
Autores principales: Nguyen, Thanh-Phuong, Liu, Wei-chung, Jordán, Ferenc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3231966/
https://www.ncbi.nlm.nih.gov/pubmed/22034985
http://dx.doi.org/10.1186/1752-0509-5-179