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Inferring pleiotropy by network analysis: linked diseases in the human PPI network
BACKGROUND: Earlier, we identified proteins connecting different disease proteins in the human protein-protein interaction network and quantified their mediator role. An analysis of the networks of these mediators shows that proteins connecting heart disease and diabetes largely overlap with the one...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3231966/ https://www.ncbi.nlm.nih.gov/pubmed/22034985 http://dx.doi.org/10.1186/1752-0509-5-179 |