Investigation of formulation variables affecting the properties of lamotrigine nanosuspension using fractional factorial design

BACKGROUND AND THE PURPOSE OF THE STUDY: Lamotrigine (LMG) undergoes extensive hepatic metabolism upon oral administration and its absorption is affected in the presence of food. This study was aimed to develop nanosuspension of LMG and investigate its formulation characteristics using L(9) orthogon...

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Detalles Bibliográficos
Autores principales: B., Mishra, N., Arya, S., Tiwari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232085/
https://www.ncbi.nlm.nih.gov/pubmed/22615586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232085/
https://www.ncbi.nlm.nih.gov/pubmed/22615586

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