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Investigation of formulation variables affecting the properties of lamotrigine nanosuspension using fractional factorial design
BACKGROUND AND THE PURPOSE OF THE STUDY: Lamotrigine (LMG) undergoes extensive hepatic metabolism upon oral administration and its absorption is affected in the presence of food. This study was aimed to develop nanosuspension of LMG and investigate its formulation characteristics using L(9) orthogon...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Tehran University of Medical Sciences
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232085/ https://www.ncbi.nlm.nih.gov/pubmed/22615586 |