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Development of novel budesonide pellets based on CODES(TM) technology: In vitro/in vivo evaluation in induced colitis in rats

BACKGROUND AND THE PURPOSE OF THE STUDY: Budesonide is the drug of choice for treatment of active inflammatory bowel disease (IBD). The aim of this study was to develop budesonide pellets based on a novel colon drug delivery system (CODES). METHODS: Pellet cores containing lactulose or mannitol were...

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Detalles Bibliográficos
Autores principales: Varshosaz, J., Emami, J., Tavakoli, N., Minaiyan, M., Rahmani, N., Dorkoosh, F., Mahzouni, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232096/
https://www.ncbi.nlm.nih.gov/pubmed/22615647