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In vivo bioavailability studies of sumatriptan succinate buccal tablets

BACK GROUND AND THE PURPOSE OF STUDY: Sumatriptan succinate is a Serotonin 5- HT1 receptor agonist, used in treatment of migraine. It is absorbed rapidly but incompletely when given orally and undergoes first-pass metabolism, resulting in a low absolute bioavailability of about 15%. The aim of this...

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Detalles Bibliográficos
Autores principales: Shivanand, K, Raju, SA, Nizamuddin, S, Jayakar, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232104/
https://www.ncbi.nlm.nih.gov/pubmed/22615661