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Chimeric aptamers in cancer cell-targeted drug delivery

Aptamers are single-stranded structured oligonucleotides (DNA or RNA) that can bind to a wide range of targets ("apatopes") with high affinity and specificity. These nucleic acid ligands, generated from pools of random-sequence by an in vitro selection process referred to as systematic evo...

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Detalles Bibliográficos
Autores principales: Kanwar, Jagat R, Roy, Kislay, Kanwar, Rupinder K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa Healthcare 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233271/
https://www.ncbi.nlm.nih.gov/pubmed/21955150
http://dx.doi.org/10.3109/10409238.2011.614592