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Enhanced Differentiation of Three-Gene-Reprogrammed Induced Pluripotent Stem Cells into Adipocytes via Adenoviral-Mediated PGC-1α Overexpression

Induced pluripotent stem cells formed by the introduction of only three factors, Oct4/Sox2/Klf4 (3-gene iPSCs), may provide a safer option for stem cell-based therapy than iPSCs conventionally introduced with four-gene iPSCs. Peroxisome proliferator-activated receptor gamma coactivator-1α (PGC-1α) p...

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Detalles Bibliográficos
Autores principales: Huang, Pin-I, Chou, Yueh-Ching, Chang, Yuh-Lih, Chien, Yueh, Chen, Kuan-Hsuan, Song, Wen-Shin, Peng, Chi-Hsien, Chang, Chin-Hong, Lee, Shin-Da, Lu, Kai-Hsi, Chen, Yi-Jen, Kuo, Chia-Hua, Hsu, Chuan-Chih, Lee, Hsin-Chen, Yung, Ming-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233422/
https://www.ncbi.nlm.nih.gov/pubmed/22174616
http://dx.doi.org/10.3390/ijms12117554