Tunicamycin Depresses P-Glycoprotein Glycosylation Without an Effect on Its Membrane Localization and Drug Efflux Activity in L1210 Cells

P-glycoprotein (P-gp), also known as ABCB1, is a member of the ABC transporter family of proteins. P-gp is an ATP-dependent drug efflux pump that is localized to the plasma membrane of mammalian cells and confers multidrug resistance in neoplastic cells. P-gp is a 140-kDa polypeptide that is glycosy...

Descripción completa

Detalles Bibliográficos
Autores principales: Šereš, Mário, Cholujová, Dana, Bubenčíkova, Tatiana, Breier, Albert, Sulová, Zdenka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233437/
https://www.ncbi.nlm.nih.gov/pubmed/22174631
http://dx.doi.org/10.3390/ijms12117772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233437/
https://www.ncbi.nlm.nih.gov/pubmed/22174631
http://dx.doi.org/10.3390/ijms12117772

Ejemplares similares