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Classical scrapie prions in ovine blood are associated with B lymphocytes and platelet-rich plasma

BACKGROUND: Classical scrapie is a naturally occurring transmissible spongiform encephalopathy of sheep and goats characterized by cellular accumulation of abnormal isoforms of prion protein (PrP(Sc)) in the central nervous system and the follicles of peripheral lymphoid tissues. Previous studies ha...

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Detalles Bibliográficos
Autores principales: Dassanayake, Rohana P, Schneider, David A, Truscott, Thomas C, Young, Alan J, Zhuang, Dongyue, O'Rourke, Katherine I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233507/
https://www.ncbi.nlm.nih.gov/pubmed/22112371
http://dx.doi.org/10.1186/1746-6148-7-75