Aldose reductase deficiency in mice protects from ragweed pollen extract (RWE)-induced allergic asthma

BACKGROUND: Childhood hospitalization related to asthma remains at historically high levels, and its incidence is on the rise world-wide. Previously, we have demonstrated that aldose reductase (AR), a regulatory enzyme of polyol pathway, is a major mediator of allergen-induced asthma pathogenesis in...

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Detalles Bibliográficos
Autores principales: Yadav, Umesh CS, Aguilera-Aguirre, Leopoldo, Boldogh, Istvan, Ramana, Kota V, Srivastava, Satish K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233521/
https://www.ncbi.nlm.nih.gov/pubmed/22054012
http://dx.doi.org/10.1186/1465-9921-12-145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233521/
https://www.ncbi.nlm.nih.gov/pubmed/22054012
http://dx.doi.org/10.1186/1465-9921-12-145

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