Cargando…
Aldose reductase deficiency in mice protects from ragweed pollen extract (RWE)-induced allergic asthma
BACKGROUND: Childhood hospitalization related to asthma remains at historically high levels, and its incidence is on the rise world-wide. Previously, we have demonstrated that aldose reductase (AR), a regulatory enzyme of polyol pathway, is a major mediator of allergen-induced asthma pathogenesis in...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233521/ https://www.ncbi.nlm.nih.gov/pubmed/22054012 http://dx.doi.org/10.1186/1465-9921-12-145 |