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A Simple but Highly Effective Approach to Evaluate the Prognostic Performance of Gene Expression Signatures
BACKGROUND: Highly parallel analysis of gene expression has recently been used to identify gene sets or ‘signatures’ to improve patient diagnosis and risk stratification. Once a signature is generated, traditional statistical testing is used to evaluate its prognostic performance. However, due to th...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233554/ https://www.ncbi.nlm.nih.gov/pubmed/22163293 http://dx.doi.org/10.1371/journal.pone.0028320 |