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A Simple but Highly Effective Approach to Evaluate the Prognostic Performance of Gene Expression Signatures

BACKGROUND: Highly parallel analysis of gene expression has recently been used to identify gene sets or ‘signatures’ to improve patient diagnosis and risk stratification. Once a signature is generated, traditional statistical testing is used to evaluate its prognostic performance. However, due to th...

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Detalles Bibliográficos
Autores principales: Starmans, Maud H. W., Fung, Glenn, Steck, Harald, Wouters, Bradly G., Lambin, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233554/
https://www.ncbi.nlm.nih.gov/pubmed/22163293
http://dx.doi.org/10.1371/journal.pone.0028320