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Role of NADPH Oxidase versus Neutrophil Proteases in Antimicrobial Host Defense
NADPH oxidase is a crucial enzyme in mediating antimicrobial host defense and in regulating inflammation. Patients with chronic granulomatous disease, an inherited disorder of NADPH oxidase in which phagocytes are defective in generation of reactive oxidant intermediates (ROIs), suffer from life-thr...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233573/ https://www.ncbi.nlm.nih.gov/pubmed/22163282 http://dx.doi.org/10.1371/journal.pone.0028149 |