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Transient Increase in Zn(2+) in Hippocampal CA1 Pyramidal Neurons Causes Reversible Memory Deficit

The translocation of synaptic Zn(2+) to the cytosolic compartment has been studied to understand Zn(2+) neurotoxicity in neurological diseases. However, it is unknown whether the moderate increase in Zn(2+) in the cytosolic compartment affects memory processing in the hippocampus. In the present stu...

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Detalles Bibliográficos
Autores principales: Takeda, Atsushi, Takada, Shunsuke, Nakamura, Masatoshi, Suzuki, Miki, Tamano, Haruna, Ando, Masaki, Oku, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233599/
https://www.ncbi.nlm.nih.gov/pubmed/22163318
http://dx.doi.org/10.1371/journal.pone.0028615