A Hepatocyte Growth Factor Receptor (Met)–Insulin Receptor hybrid governs hepatic glucose metabolism

Met is the transmembrane tyrosine kinase cell surface receptor for Hepatocyte Growth Factor (HGF) and is related to the insulin receptor (INSR) tyrosine kinase. Here we report that the HGF–Met axis controls metabolism by stimulating hepatic glucose uptake and suppressing hepatic glucose output. We s...

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Detalles Bibliográficos
Autores principales: Fafalios, Arlee, Ma, Jihong, Tan, Xinping, Stoops, John, Luo, Jianhua, DeFrances, Marie C., Zarnegar, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233634/
https://www.ncbi.nlm.nih.gov/pubmed/22081023
http://dx.doi.org/10.1038/nm.2531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233634/
https://www.ncbi.nlm.nih.gov/pubmed/22081023
http://dx.doi.org/10.1038/nm.2531

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