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Effects of raising muscle glycogen synthesis rate on skeletal muscle ATP turnover rate in type 2 diabetes

Mitochondrial dysfunction has been implicated in the pathogenesis of type 2 diabetes. We hypothesized that any impairment in insulin-stimulated muscle ATP production could merely reflect the lower rates of muscle glucose uptake and glycogen synthesis, rather than cause it. If this is correct, muscle...

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Detalles Bibliográficos
Autores principales: Lim, Ee L., Hollingsworth, Kieren G., Smith, Fiona E., Thelwall, Peter E., Taylor, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233777/
https://www.ncbi.nlm.nih.gov/pubmed/21917633
http://dx.doi.org/10.1152/ajpendo.00278.2011