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Pegylated liposomal doxorubicin (PLD): enhanced skin toxicity in areas of vitiligo

Pegylated liposomal doxorubicin (PLD, Doxil, Caelyx) is widely used for the treatment of ovarian cancer. It is a stable formulation encapsulating doxorubicin in a ‘Stealth’ (i.e., pegylated) liposome with a half-life of about 72 hours. This drastically altered pharmacology confers on it a considerab...

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Detalles Bibliográficos
Autores principales: Yuan, Y, Orlow, SJ, Curtin, J, Downey, A, Muggia, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234058/
https://www.ncbi.nlm.nih.gov/pubmed/22275986
http://dx.doi.org/10.3332/ecancer.2008.111