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Co-existence of breast and ovarian cancers in BRCA germ-line mutation carriers

The co-existence of breast and ovarian cancers in the same individual should raise suspicion of a hereditary process. Patients with either BRCA1 or BRCA2 germ-line mutations have an average risk of 39% and 11% respectively of developing ovarian cancer by the age of 70; they have a risk of 35–85% of...

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Detalles Bibliográficos
Autores principales: Dilawari, A, Cangiarella, J, Smith, J, Huang, A, Downey, A, Muggia, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234065/
https://www.ncbi.nlm.nih.gov/pubmed/22275985
http://dx.doi.org/10.3332/ecancer.2008.109